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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PBK
All Species:
26.36
Human Site:
Y74
Identified Species:
44.62
UniProt:
Q96KB5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KB5
NP_060962.2
322
36085
Y74
N
P
I
C
N
D
H
Y
R
S
V
Y
Q
K
R
Chimpanzee
Pan troglodytes
XP_520045
322
36011
Y74
N
P
I
C
D
D
H
Y
R
S
V
Y
Q
K
R
Rhesus Macaque
Macaca mulatta
XP_001109768
323
36123
Y74
N
P
I
C
N
D
H
Y
R
S
V
Y
Q
K
R
Dog
Lupus familis
XP_534564
324
36430
Y74
N
P
K
C
N
D
H
Y
Q
S
M
Y
Q
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ78
330
36726
R74
L
L
C
D
D
H
Y
R
T
V
Y
Q
K
R
L
Rat
Rattus norvegicus
NP_001073406
337
37551
Y74
N
P
L
C
D
D
H
Y
R
T
V
Y
Q
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508951
321
35996
Y74
N
P
K
C
D
D
H
Y
Q
S
I
Y
Q
K
R
Chicken
Gallus gallus
XP_420011
322
35395
S74
N
Q
Q
N
I
Y
Q
S
R
L
N
E
E
A
K
Frog
Xenopus laevis
NP_001088960
325
36517
S75
S
K
L
C
D
A
S
S
R
N
L
Y
E
H
R
Zebra Danio
Brachydanio rerio
Q6DHU8
339
37645
Q77
N
S
K
C
A
Q
G
Q
V
S
V
Y
Q
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573239
398
44994
E77
K
K
D
T
L
F
N
E
R
I
V
H
E
A
D
Honey Bee
Apis mellifera
XP_623765
343
38973
K74
N
S
K
I
V
K
D
K
K
Y
N
E
R
I
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798752
344
37735
R95
R
S
K
Y
K
K
G
R
G
D
V
D
V
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130276
278
30401
P39
L
D
A
A
K
I
G
P
A
A
L
E
A
E
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
93.5
N.A.
85.4
86.3
N.A.
83.2
73.5
70.1
64
N.A.
35.9
41.4
N.A.
46.5
Protein Similarity:
100
99.6
98.7
96.9
N.A.
92.4
91.9
N.A.
89.7
85.4
85.2
77.2
N.A.
51.2
58.8
N.A.
63.9
P-Site Identity:
100
93.3
100
80
N.A.
0
80
N.A.
73.3
13.3
26.6
53.3
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
100
N.A.
93.3
26.6
66.6
53.3
N.A.
33.3
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
26.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
45.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
0
0
8
8
0
0
8
15
8
% A
% Cys:
0
0
8
58
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
36
43
8
0
0
8
0
8
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
22
22
15
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
22
0
8
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
8
43
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
22
8
8
8
0
0
0
8
8
0
0
8
0
% I
% Lys:
8
15
36
0
15
15
0
8
8
0
0
0
8
50
8
% K
% Leu:
15
8
15
0
8
0
0
0
0
8
15
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
65
0
0
8
22
0
8
0
0
8
15
0
0
0
0
% N
% Pro:
0
43
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
8
8
8
15
0
0
8
50
0
8
% Q
% Arg:
8
0
0
0
0
0
0
15
50
0
0
0
8
8
58
% R
% Ser:
8
22
0
0
0
0
8
15
0
43
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
8
8
50
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
43
0
8
8
58
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _